This segment of interstate I-80 reaches from Reno, Nevada to Sacramento, California, crossing Donner Pass.
Interstate I-10 reaches from Roadforks, near the border of Arizona, to Anthony, near the border of Texas near El Paso.
Interstate I-10 reaches from California to Florida and passes through Arizona, New Mexico, Texas, Louisiana, Mississippi, and Alabama.
Interstate I-15 reaches from Canada to Mexico and passes through Montana, Idaho, Utah, Arizona, Nevada, and California.
Interstate I-20 reaches from Texas to South Carolina and passes through Louisiana, Mississippi, Alabama, and Georgia.
Interstate I-25 reaches from Wyoming to New Mexico and passes through Colorado.
Interstate I-29 reaches from Canada to Missouri and passes through North Dakota, South Dakota, and Iowa.
Interstate I-30 reaches from Texas to Arkansas.
Interstate I-35 reaches from Minnesota to Texas and passes through Iowa, Missouri, Kansas, and Oklahoma.
Interstate I-40 reaches from California to North Carolina and passes through Arizona, New Mexico, Texas, Oklahoma, Arkansas, and Tennessee.
Interstate I-44 reaches from Missouri to Texas and passes through Oklahoma.
Interstate I-45 is located entirely within Texas, stretching from Dallas to the Gulf Coast.
Interstate I-5 reaches from Canada to Mexico and passes through Washington, Oregon, and California.
Interstate I-55 reaches from Illinois to Louisiana and passes through Missouri, Tennessee, Arkansas, and Mississippi.
Interstate I-59 reaches from Georgia to Louisiana and passes through Alabama and Mississippi.
Interstate I-64 reaches from Missouri to Virginia and passes through Illinois, Indiana, Kentucky, and West Virginia.
Interstate I-65 reaches from Indiana to Alabama and passes through Kentucky and Tennessee.
Interstate I-70 reaches from Utah to Maryland and passes through Colorado, Kansas, Missouri, Illinois, Indiana, Ohio, West Virginia, and Pennsylvania.
This segment of interstate I-74 reaches from Iowa to Ohio and passes through Illinois and Indiana.
This segment of interstate I-55 exists entirely within North Carolina.
Interstate I-75 reaches from Canada to Florida and passes through Michigan, Ohio, Kentucky, Tennessee, and Georgia.
This segment of interstate I-76 reaches from Colorado to Nebraska.
This segment of interstate I-76 reaches from Ohio to New Jersey and passes through Pennsylvania.
Interstate I-77 reaches from Ohio to South Carolina and passes through West Virginia, Virginia, and North Carolina.
Interstate I-80 reaches from California to New Jersey and passes through Nevada, Utah, Wyoming, Nebraska, Iowa, Illinois, Indiana, Ohio, and Pennsylvania.
Interstate I-80 in Wyoming reaches from Evanston, on the border of Utah, to Pine Bluffs, on the border of Nebraska, and passes through Laramie and Cheyenne.
Interstate I-81 reaches from Canada to Tennessee and passes through New York, Pennsylvania, Maryland, West Virginia, and Virginia.
This segment of interstate I-84 reaches from Oregon to Utah and passes through Idaho.
This segment of interstate I-84 reaches from Pennsylvania to Massachusetts and passes through New York and Connecticut.
Interstate I-85 reaches from Virginia to Alabama and passes through North Carolina, South Carolina, and Georgia.
Interstate I-87 exists entirely within New York, reaching from New York City to Canada.
Interstate I-90 reaches from Washington to Massachusetts and passes through Idaho, Montana, Wyoming, South Dakota, Minnesota, Wisconsin, Illinois, Indiana, Ohio, Pennsylvania, and New York.
Interstate I-91 reaches from Canada to Connecticut and passes through Vermont and Massachusetts.
Interstate I-94 reaches from Montana to Michigan and passes through North Dakota, Minnesota, Wisconsin, Illinois, and Indiana.
Interstate I-95 reaches from Canada to Florida and passes through Maine, New Hampshire, Massachusetts, Rhode Island, Connecticut, New York, New Jersey, Pennsylvania, Delaware, Maryland, Virginia, North Carolina, South Carolina, and Georgia.
Québec Autoroute 20 reaches from Pointe-Lalonde, Québec, to Trois-Pistoles, Québec, passing through Montreal and Québec City.
Québec Autoroute 40 reaches from Pointe-Fortune, Québec, to Boischatel, Québec, passing through Montreal and Québec City.
Alberta Highway 1 reaches from the province of British Columbia to the province of Saskatchewan, passing through Calgary.
British Columbia Highway 1 reaches from Victoria, British Columbia, to the province of Alberta, passing through Vancouver.
Manitoba Highway 1 reaches from the province of Saskatchewan to the province of Ontario, passing through Winnipeg.
Newfoundland Highway 1 reaches from Channel-Port aux Basques in the west to St. John's in the east, passing through Deer Lake, Clarenville, and Whitbourne.
Saskatchewan Highway 1 reaches from the province of Alberta to the province of Manitoba, passing through Regina.
New Brunswick Highway 104 reaches from Fort Lawrence, Nova Scotia, to River Tillard, Nova Scotia, passing through Truro, New Glasgow, Antigonish, and Port Hastings.
New Brunswick Highway 105 reaches from Port Hastings, Nova Scotia, to North Sydney, Nova Scotia, passing through Whycocomagh, Baddeck, and St. Anns.
Also known as the Highway of Tears, British Columbia Highway 16 reaches from Prince Rupert, British Columbia, to Decoigne, Alberta, passing through Prince George.
Also known as King's Highway 17, Ontario Highway 17 reaches from the province of Manitoba nearly to the province of Quebec, passing through Thunday Bay, Sault Ste. Marie, and Sudbury.
New Brunswick Highway 2 reaches from Saint-Jacques Parish, New Brunswick, to Westmorland Parish, New Brunswick, passing through Woodstock, Fredericton, and Moncton.
British Columbia Highway 3 reaches from Hope, British Columbia, to Crowsnest, Alberta, passing through Osoyoos, Grand Forks, Creston, and Cranbrook.
Known as King's Highway 417, Ontario Highway 417 reaches from Arnprior to the border of Quebec near Montreal, passing through Ottawa.
British Columbia Highway 6 reaches from Vernon, British Columbia, to Nelway, British Columbia, passing through Nakusp and Nelson.
The Trans-Canada Highway reaches coast-to-coast from Victoria, British Columbia, to St. John, New Brunswick.